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dr. L.P.G. (Lennie) Derde

dr. L.P.G. (Lennie) Derde

Assistant Professor - medical
dr. L.P.G. (Lennie) Derde
  • Intensive Care Medicine

Research Programs

Infection & Immunity

Biography

Biography

Lennie is an ICU consultant with a background in infectious diseases and epidemiology. She obtained her Ph.D. after successfully defending her thesis "Controlling antibiotic resistance in the ICU" in 2013. Her research focuses on innovative trial design, mainly in sepsis and severe infections. She is the immediate past chair of the International Trial Steering Committee of REMAP-CAP, an Adaptive Platform Trial investigating the best treatment for pneumonia, including Covid-19. Lennie is a co-applicant and work package leader on EU-funded projects RECOVER and ECRAID-Base, and co-applicant on several international collaborative grants. 

Research Output (62)

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia

Martin-Loeches Ignacio, Torres Antoni, Nagavci Blin, Aliberti Stefano, Antonelli Massimo, Bassetti Matteo, Bos Lieuwe, Chalmers James, Derde Lennie, de Waele Jan, Garnacho-Montero Jose, Kollef Marin, Luna Carlos, Menendez Rosario, Niederman Michael, Ponomarev Dimitry, Restrepo Marcos, Rigau David, Schultz Marcus, Weiss Emmanuele, Welte Tobias, Wunderink Richard Aug 2023, In: Intensive Care Medicine. 49 , p. 615-632 18 p.

Cohort profile of PLUTO:a perioperative biobank focusing on prediction and early diagnosis of postoperative complications

de Mul Nikki, Verlaan Diede, Ruurda Jelle P, van Grevenstein Wilhelmina M U, Hagendoorn Jeroen, de Borst Gert-Jan, Vriens Menno R, de Bree Remco, Zweemer Ronald P, Vogely Charles, Haitsma Mulier Jelle L G, Vernooij Lisette M, Reitsma Johannes B, de Zoete Marcel R, Top Janetta, Kluijtmans Jan A J, Hoefer Imo E, Noordzij Peter, Rettig Thijs, Marsman Marije, de Smet Anne Marie G A, Derde Lennie, van Waes Judith, Rijsdijk Mienke, Schellekens Willem Jan M, Bonten Marc J M, Slooter Arjen J C, Cremer Olaf L 19 Apr 2023, In: BMJ Open. 13 16 p.

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19:A Randomized Clinical Trial

Lawler Patrick R, Derde Lennie P G, van de Veerdonk Frank L, McVerry Bryan J, Huang David T, Berry Lindsay R, Lorenzi Elizabeth, van Kimmenade Roland, Gommans Frank, Vaduganathan Muthiah, Leaf David E, Baron Rebecca M, Kim Edy Y, Frankfurter Claudia, Epelman Slava, Kwan Yvonne, Grieve Richard, O'Neill Stephen, Sadique Zia, Puskarich Michael, Marshall John C, Higgins Alisa M, Mouncey Paul R, Rowan Kathryn M, Al-Beidh Farah, Annane Djillali, Arabi Yaseen M, Au Carly, Beane Abi, van Bentum-Puijk Wilma, Bonten Marc J M, Bradbury Charlotte A, Brunkhorst Frank M, Burrell Aidan, Buzgau Adrian, Buxton Meredith, Cecconi Maurizio, Cheng Allen C, Cove Matthew, Detry Michelle A, Estcourt Lise J, Ezekowitz Justin, Fitzgerald Mark, Gattas David, Godoy Lucas C, Goossens Herman, Haniffa Rashan, Harrison David A, Hills Thomas, Horvat Christopher M, 11 Apr 2023, In: JAMA - The Journal of The American Medical Association. 329 , p. 1183-1196 14 p.

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia

Martin-Loeches Ignacio, Torres Antoni, Nagavci Blin, Aliberti Stefano, Antonelli Massimo, Bassetti Matteo, Bos Lieuwe, Chalmers James, Derde Lennie, de Waele Jan, Garnacho-Montero Jose, Kollef Marin, Luna Carlos, Menendez Rosario, Niederman Michael, Ponomarev Dimitry, Restrepo Marcos, Rigau David, Schultz Marcus, Weiss Emmanuele, Welte Tobias, Wunderink Richard 1 Apr 2023, In: The European respiratory journal. 61

Platform trials as the way forward in infectious disease’ clinical research:the case of coronavirus disease 2019

Pericàs Juan M., Derde Lennie P.G., Berry Scott M., Mar 2023, In: Clinical Microbiology and Infection. 29 , p. 277-280 4 p.

Correction:ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia (Intensive Care Medicine, (2023), 49, 6, (615-632), 10.1007/s00134-023-07033-8)

Martin-Loeches Ignacio, Torres Antoni, Nagavci Blin, Aliberti Stefano, Antonelli Massimo, Bassetti Matteo, Bos Lieuwe D., Chalmers James D., Derde Lennie, De Waele Jan, Garnacho-Montero Jose, Kollef Marin, Luna Carlos M., Menendez Rosario, Niederman Michael S., Ponomarev Dmitry, Restrepo Marcos I., Rigau David, Schultz Marcus J., Weiss Emmanuel, Welte Tobias, Wunderink Richard 2023, In: Intensive Care Medicine. 49 , p. 1040-1041 2 p.

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial

Higgins Alisa M, Berry Lindsay R, Lorenzi Elizabeth, Murthy Srinivas, McQuilten Zoe, Mouncey Paul R, Al-Beidh Farah, Annane Djillali, Arabi Yaseen M, Beane Abi, van Bentum-Puijk Wilma, Bhimani Zahra, Bonten Marc J M, Bradbury Charlotte A, Brunkhorst Frank M, Burrell Aiden, Buzgau Adrian, Buxton Meredith, Charles Walton N, Cove Matthew, Detry Michelle A, Estcourt Lise J, Fagbodun Elizabeth O, Fitzgerald Mark, Girard Timothy D, Goligher Ewan C, Goossens Herman, Haniffa Rashan, Hills Thomas, Horvat Christopher M, Huang David T, Ichihara Nao, Lamontagne Francois, Marshall John C, McAuley Daniel F, McGlothlin Anna, McGuinness Shay P, McVerry Bryan J, Neal Matthew D, Nichol Alistair D, Parke Rachael L, Parker Jane C, Parry-Billings Karen, Peters Sam E C, Reyes Luis F, Rowan Kathryn M, Saito Hiroki, Santos Marlene S, Saunders Christina T, Derde Lennie P G, Leavis HL, 16 Dec 2022, In: JAMA - The Journal of The American Medical Association. 329 , p. 39-51 13 p.

The Renin-Angiotensin System in Acute Lung Injury∗

Lawler Patrick R., Derde Lennie P.G., Mcverry Bryan J., Russell James A., Van De Veerdonk Frank L. 1 Sep 2022, In: Critical care medicine. 50 , p. 1411-1415 5 p.

Updated competency-based training in intensive care:next step towards a healthcare union in Europe?

Póvoa Pedro, Martin-Loeches Ignacio, Duska Frantisek, Hästbacka Johanna, Gomes Ernestina, Le Roy Anne, Matsa Ramprasad, Derde Lennie, Hein Lars, Castellanos Álvaro, Roten Hans Ulrich, Aug 2022, In: Intensive Care Medicine. 48 , p. 1093-1094 2 p.

Association between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19:A network meta-analysis

Godolphin Peter J., Fisher David J., Berry Lindsay R., Derde Lennie P.G., Diaz Janet V., Gordon Anthony C., Lorenzi Elizabeth, Marshall John C., Murthy Srinivas, Shankar-Hari Manu, Sterne Jonathan A.C., Tierney Jayne F., Vale Claire L. Jul 2022, In: PLoS ONE. 17

All research output

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